MAP Kinase-Interacting Kinase 1 Regulates SMAD2-Dependent TGF-β Signaling Pathway in Human Glioblastoma
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چکیده
منابع مشابه
Tumor and Stem Cell Biology MAP Kinase-Interacting Kinase 1 Regulates SMAD2- Dependent TGF-bSignaling Pathway in HumanGlioblastoma
Glioblastoma multiforme (GBM) is the most common aggressive brain cancer with a median survival of approximately 1 year. In a search for novel molecular targets that could be therapeutically developed, our kinome-focused microarray analysis identified the MAP (mitogen-activated protein) kinase-interacting kinase 1 (MNK1) as an attractive theranostic candidate. MNK1 overexpression was confirmed ...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2011
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-10-3112